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· Dermal Fillers
SKU 11104

Restylane Refyne Lidocaine

Restylane Refyne Lidocaine is a dermal filler for the correction of moderate to severe facial wrinkles and folds. It targets nasolabial folds, marionette lines, and other dynamic lower-face creases while preserving natural facial expression.

In stock
Volume
1 x 1 mL
Laboratory
Galderma Laboratories, L.P.
Origin
Sweden
Indication
Moderate to severe wrinkles, dynamic lower-face lines
Trade price and history are verified-only
allpara supplies licensed practitioners. Sign in or apply for a B2B account to see live pricing, volume tiers and price history.

Restylane Refyne Lidocaine is a soft, flexible hyaluronic acid filler from Galderma, formulated to smooth moderate to severe facial wrinkles while preserving natural expression. It is regularly selected by clinics, dermatologists and aesthetic physicians for nasolabial folds and dynamic lower-face lines. The gel is crosslinked sodium hyaluronate at 20 mg/mL with 3 mg/mL lidocaine hydrochloride for comfort, and it is supplied for professional use only.

Key Benefits of Restylane Refyne Lidocaine

  • Formulated for flexibility in dynamic facial areas, so treated skin still moves with expression
  • Softer gel with moderate lifting capacity, aimed at refined correction rather than structural change
  • Corrects moderate to severe facial wrinkles and folds, such as nasolabial folds, in patients over the age of 21
  • Sterile, biodegradable, viscoelastic, non-pyrogenic, clear, colourless and homogeneous soft gel
  • Contains lidocaine hydrochloride 3 mg/mL, so no separate anaesthetic is needed at the site
  • Sodium hyaluronate at 20 mg/mL in phosphate-buffered saline at pH 7
  • Injected with a 30G needle for contouring and volumising of facial wrinkles and folds
Key Information
Brand RESTYLANE
Manufacturer Galderma
Country of Origin Sweden
Certification CE marked in the EU since 2010, originally under the brand name Emervel Classic Lidocaine, in accordance with Regulation (EU) 2017/745. The needles supplied are CE marked 0123
Ingredients Sterile, biodegradable, viscoelastic, non-pyrogenic, clear, colourless and homogeneous soft hyaluronic acid gel with a moderate lifting capacity, in phosphate-buffered saline at pH 7. Sodium hyaluronate 20 mg/mL with lidocaine hydrochloride 3 mg/mL
Volume / Size 1 ml
Packaging 1 x 1 mL prefilled syringe, supplied with needles as stated on the carton
Needle Size 30G
Use Type For professional use. Injectable dermal filler
Injection Depth Mid-to-deep dermis

Indications and Professional Use

Main indications

  • Moderate to severe facial wrinkles and folds, such as nasolabial folds, in patients over the age of 21, by injection into the mid-to-deep dermis

Professional use

Restylane Refyne Lidocaine is an injectable medical device for administration only by licensed, appropriately trained healthcare practitioners in a controlled clinical setting, and is not for retail sale or self-administration. It is indicated for injection into the mid-to-deep dermis for the correction of moderate to severe facial wrinkles and folds in patients over the age of 21, injected using a 30G needle for contouring and volumising. Introduction into the vasculature may lead to embolisation, occlusion of the vessels, ischaemia, or infarction, so the product should be injected slowly and with the least amount of pressure necessary. Failure to comply with the needle attachment instructions could result in needle disengagement or product leakage at the Luer lock and needle hub connection.

Treatment areas

  • Nasolabial folds
  • Moderate to severe facial wrinkles and folds

Patient profile

For patients over the age of 21 assessed as suitable by the treating practitioner. Patient selection, treatment area, injected volume and injection plane follow the practitioner's clinical assessment, with this reference suited to patients whose concern is moderate wrinkling in mobile areas rather than loss of facial structure. Because the gel contains lidocaine hydrochloride 3 mg/mL, patients with known hypersensitivity to lidocaine or to amide-type local anaesthetics must not receive it. It is contraindicated in patients with severe allergies manifested by a history of anaphylaxis, or a history or presence of multiple severe allergies, and in patients with a history of allergy to gram-positive bacterial proteins, since the gel may contain trace amounts of such material.

How Restylane Refyne Lidocaine Works

Restylane Refyne Lidocaine works through crosslinked sodium hyaluronate formulated as a soft, flexible gel, so when placed in the mid to deep dermis it supports the fold without stiffening the tissue around it. That flexibility is the point: in the mobile lower face a firmer gel can read as unnatural on movement. The incorporated lidocaine hydrochloride reduces discomfort during injection and plays no part in the correction.

Why Order From Allpara

Allpara offers genuine, verified RESTYLANE products from vetted suppliers, with full batch-traceability and expert support. We serve clinics and aesthetic professionals with CE-certified products, fast EU-wide delivery from our EU warehouse, and competitive trade pricing. Our focus is your patients' safety, satisfaction and results - with dedicated after-sales support for your peace of mind.

Frequently Asked Questions

How does Restylane Refyne Lidocaine differ from Defyne?

Both carry 20 mg/mL sodium hyaluronate with lidocaine hydrochloride 3 mg/mL, so the difference is not concentration. Refyne is the softer, more flexible gel intended for moderate to severe wrinkles in dynamic areas and is injected with a 30G needle. Defyne is firmer, aimed at severe wrinkles and folds including marionette lines, and is supplied with 27G needles. The reference is chosen by depth of correction and the mobility of the area, not interchangeably.

Why is flexibility important for this filler?

Restylane Refyne Lidocaine is a soft gel with moderate lifting capacity, formulated to provide subtle support in dynamic facial areas while allowing natural movement and expression. In the mobile lower face that flexibility is what keeps the result looking natural when the patient speaks or smiles, which is why a firmer structural gel is not a substitute here.

How do clinics order Restylane Refyne Lidocaine wholesale?

ALLPARA supplies Restylane Refyne Lidocaine to licensed practitioners, clinics and distributors on a B2B account. Refyne and Defyne are commonly stocked together since they cover different depths of correction, so tell us which you need and in what quantity. Wholesale terms, stock position and batch expiry are released to registered professional buyers.

/ Specifications

The datasheet

Category
Dermal Fillers
Brand
RESTYLANE
Laboratory
Galderma Laboratories, L.P.
SKU
11104
Format
1 x 1 mL
Origin
Sweden
Indication
Moderate to severe wrinkles, dynamic lower-face lines
Use
Professional use
Attributes
/ Product details

The full file

Restylane Refyne Lidocaine is a soft, flexible hyaluronic acid filler from Galderma, formulated to smooth moderate to severe facial wrinkles while preserving natural expression. It is regularly selected by clinics, dermatologists and aesthetic physicians for nasolabial folds and dynamic lower-face lines. The gel is crosslinked sodium hyaluronate at 20 mg/mL with 3 mg/mL lidocaine hydrochloride for comfort, and it is supplied for professional use only.

Galderma Laboratories, L.P., country of origin Sweden.

Shipped EU-wide from our EU warehouse, tracked and insured, with 24-72h dispatch. Each unit ships with batch number and expiry, held in EU bond and batch-traceable.

Store to manufacturer specification, away from direct light. Cold-chain is only used where the product requires it.

Net 30 / 60 / 90 day terms* are available to verified accounts on credit approval. Invoicing is supported in EUR, CHF and GBP.

Terms are indicative and confirmed after account review.

How does Restylane Refyne Lidocaine differ from Defyne?

Both carry 20 mg/mL sodium hyaluronate with lidocaine hydrochloride 3 mg/mL, so the difference is not concentration. Refyne is the softer, more flexible gel intended for moderate to severe wrinkles in dynamic areas and is injected with a 30G needle. Defyne is firmer, aimed at severe wrinkles and folds including marionette lines, and is supplied with 27G needles. The reference is chosen by depth of correction and the mobility of the area, not interchangeably.

Why is flexibility important for this filler?

Restylane Refyne Lidocaine is a soft gel with moderate lifting capacity, formulated to provide subtle support in dynamic facial areas while allowing natural movement and expression. In the mobile lower face that flexibility is what keeps the result looking natural when the patient speaks or smiles, which is why a firmer structural gel is not a substitute here.

How do clinics order Restylane Refyne Lidocaine wholesale?

ALLPARA supplies Restylane Refyne Lidocaine to licensed practitioners, clinics and distributors on a B2B account. Refyne and Defyne are commonly stocked together since they cover different depths of correction, so tell us which you need and in what quantity. Wholesale terms, stock position and batch expiry are released to registered professional buyers.

/ Quick answers

Everything a buyer asks first

How does Restylane Refyne Lidocaine differ from Defyne?
Both carry 20 mg/mL sodium hyaluronate with lidocaine hydrochloride 3 mg/mL, so the difference is not concentration. Refyne is the softer, more flexible gel intended for moderate to severe wrinkles in dynamic areas and is injected with a 30G needle. Defyne is firmer, aimed at severe wrinkles and folds including marionette lines, and is supplied with 27G needles. The reference is chosen by depth of correction and the mobility of the area, not interchangeably.
Why is flexibility important for this filler?
Restylane Refyne Lidocaine is a soft gel with moderate lifting capacity, formulated to provide subtle support in dynamic facial areas while allowing natural movement and expression. In the mobile lower face that flexibility is what keeps the result looking natural when the patient speaks or smiles, which is why a firmer structural gel is not a substitute here.
How do clinics order Restylane Refyne Lidocaine wholesale?
ALLPARA supplies Restylane Refyne Lidocaine to licensed practitioners, clinics and distributors on a B2B account. Refyne and Defyne are commonly stocked together since they cover different depths of correction, so tell us which you need and in what quantity. Wholesale terms, stock position and batch expiry are released to registered professional buyers.
/ FAQ

Frequently asked

Both carry 20 mg/mL sodium hyaluronate with lidocaine hydrochloride 3 mg/mL, so the difference is not concentration. Refyne is the softer, more flexible gel intended for moderate to severe wrinkles in dynamic areas and is injected with a 30G needle. Defyne is firmer, aimed at severe wrinkles and folds including marionette lines, and is supplied with 27G needles. The reference is chosen by depth of correction and the mobility of the area, not interchangeably.
Restylane Refyne Lidocaine is a soft gel with moderate lifting capacity, formulated to provide subtle support in dynamic facial areas while allowing natural movement and expression. In the mobile lower face that flexibility is what keeps the result looking natural when the patient speaks or smiles, which is why a firmer structural gel is not a substitute here.
ALLPARA supplies Restylane Refyne Lidocaine to licensed practitioners, clinics and distributors on a B2B account. Refyne and Defyne are commonly stocked together since they cover different depths of correction, so tell us which you need and in what quantity. Wholesale terms, stock position and batch expiry are released to registered professional buyers.

More from Galderma

View laboratory

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Restylane Refyne Lidocaine

In stock
Verified-only pricing
Sign in or apply for a B2B account to see your price.
Apply for B2B

Restylane Refyne Lidocaine is a soft, flexible hyaluronic acid filler from Galderma, formulated to smooth moderate to severe facial wrinkles while preserving natural expression. It is regularly selected by clinics, dermatologists and aesthetic physicians for nasolabial folds and dynamic lower-face lines. The gel is crosslinked sodium hyaluronate at 20 mg/mL with 3 mg/mL lidocaine hydrochloride for comfort, and it is supplied for professional use only.

Key Benefits of Restylane Refyne Lidocaine

  • Formulated for flexibility in dynamic facial areas, so treated skin still moves with expression
  • Softer gel with moderate lifting capacity, aimed at refined correction rather than structural change
  • Corrects moderate to severe facial wrinkles and folds, such as nasolabial folds, in patients over the age of 21
  • Sterile, biodegradable, viscoelastic, non-pyrogenic, clear, colourless and homogeneous soft gel
  • Contains lidocaine hydrochloride 3 mg/mL, so no separate anaesthetic is needed at the site
  • Sodium hyaluronate at 20 mg/mL in phosphate-buffered saline at pH 7
  • Injected with a 30G needle for contouring and volumising of facial wrinkles and folds
Key Information
Brand RESTYLANE
Manufacturer Galderma
Country of Origin Sweden
Certification CE marked in the EU since 2010, originally under the brand name Emervel Classic Lidocaine, in accordance with Regulation (EU) 2017/745. The needles supplied are CE marked 0123
Ingredients Sterile, biodegradable, viscoelastic, non-pyrogenic, clear, colourless and homogeneous soft hyaluronic acid gel with a moderate lifting capacity, in phosphate-buffered saline at pH 7. Sodium hyaluronate 20 mg/mL with lidocaine hydrochloride 3 mg/mL
Volume / Size 1 ml
Packaging 1 x 1 mL prefilled syringe, supplied with needles as stated on the carton
Needle Size 30G
Use Type For professional use. Injectable dermal filler
Injection Depth Mid-to-deep dermis

Indications and Professional Use

Main indications

  • Moderate to severe facial wrinkles and folds, such as nasolabial folds, in patients over the age of 21, by injection into the mid-to-deep dermis

Professional use

Restylane Refyne Lidocaine is an injectable medical device for administration only by licensed, appropriately trained healthcare practitioners in a controlled clinical setting, and is not for retail sale or self-administration. It is indicated for injection into the mid-to-deep dermis for the correction of moderate to severe facial wrinkles and folds in patients over the age of 21, injected using a 30G needle for contouring and volumising. Introduction into the vasculature may lead to embolisation, occlusion of the vessels, ischaemia, or infarction, so the product should be injected slowly and with the least amount of pressure necessary. Failure to comply with the needle attachment instructions could result in needle disengagement or product leakage at the Luer lock and needle hub connection.

Treatment areas

  • Nasolabial folds
  • Moderate to severe facial wrinkles and folds

Patient profile

For patients over the age of 21 assessed as suitable by the treating practitioner. Patient selection, treatment area, injected volume and injection plane follow the practitioner's clinical assessment, with this reference suited to patients whose concern is moderate wrinkling in mobile areas rather than loss of facial structure. Because the gel contains lidocaine hydrochloride 3 mg/mL, patients with known hypersensitivity to lidocaine or to amide-type local anaesthetics must not receive it. It is contraindicated in patients with severe allergies manifested by a history of anaphylaxis, or a history or presence of multiple severe allergies, and in patients with a history of allergy to gram-positive bacterial proteins, since the gel may contain trace amounts of such material.

How Restylane Refyne Lidocaine Works

Restylane Refyne Lidocaine works through crosslinked sodium hyaluronate formulated as a soft, flexible gel, so when placed in the mid to deep dermis it supports the fold without stiffening the tissue around it. That flexibility is the point: in the mobile lower face a firmer gel can read as unnatural on movement. The incorporated lidocaine hydrochloride reduces discomfort during injection and plays no part in the correction.

Why Order From Allpara

Allpara offers genuine, verified RESTYLANE products with full batch-traceability, CE-certified stock, fast EU-wide delivery and expert after-sales support.

Frequently Asked Questions

How does Restylane Refyne Lidocaine differ from Defyne?

Both carry 20 mg/mL sodium hyaluronate with lidocaine hydrochloride 3 mg/mL, so the difference is not concentration. Refyne is the softer, more flexible gel intended for moderate to severe wrinkles in dynamic areas and is injected with a 30G needle. Defyne is firmer, aimed at severe wrinkles and folds including marionette lines, and is supplied with 27G needles. The reference is chosen by depth of correction and the mobility of the area, not interchangeably.

Why is flexibility important for this filler?

Restylane Refyne Lidocaine is a soft gel with moderate lifting capacity, formulated to provide subtle support in dynamic facial areas while allowing natural movement and expression. In the mobile lower face that flexibility is what keeps the result looking natural when the patient speaks or smiles, which is why a firmer structural gel is not a substitute here.

How do clinics order Restylane Refyne Lidocaine wholesale?

ALLPARA supplies Restylane Refyne Lidocaine to licensed practitioners, clinics and distributors on a B2B account. Refyne and Defyne are commonly stocked together since they cover different depths of correction, so tell us which you need and in what quantity. Wholesale terms, stock position and batch expiry are released to registered professional buyers.

More from Galderma

View laboratory →

Restylane Refyne Lidocaine is a soft, flexible hyaluronic acid filler from Galderma, formulated to smooth moderate to severe facial wrinkles while preserving natural expression. It is regularly selected by clinics, dermatologists and aesthetic physicians for nasolabial folds and dynamic lower-face lines. The gel is crosslinked sodium hyaluronate at 20 mg/mL with 3 mg/mL lidocaine hydrochloride for comfort, and it is supplied for professional use only.

Galderma Laboratories, L.P., country of origin Sweden.

Shipped EU-wide from our EU warehouse, 24-72h dispatch, tracked and insured. Each unit ships with batch number and expiry, held in EU bond and batch-traceable. Store to manufacturer specification.

Net 30 / 60 / 90 day terms* for verified accounts on credit approval. Invoicing in EUR, CHF and GBP.

How does Restylane Refyne Lidocaine differ from Defyne?

Both carry 20 mg/mL sodium hyaluronate with lidocaine hydrochloride 3 mg/mL, so the difference is not concentration. Refyne is the softer, more flexible gel intended for moderate to severe wrinkles in dynamic areas and is injected with a 30G needle. Defyne is firmer, aimed at severe wrinkles and folds including marionette lines, and is supplied with 27G needles. The reference is chosen by depth of correction and the mobility of the area, not interchangeably.

Why is flexibility important for this filler?

Restylane Refyne Lidocaine is a soft gel with moderate lifting capacity, formulated to provide subtle support in dynamic facial areas while allowing natural movement and expression. In the mobile lower face that flexibility is what keeps the result looking natural when the patient speaks or smiles, which is why a firmer structural gel is not a substitute here.

How do clinics order Restylane Refyne Lidocaine wholesale?

ALLPARA supplies Restylane Refyne Lidocaine to licensed practitioners, clinics and distributors on a B2B account. Refyne and Defyne are commonly stocked together since they cover different depths of correction, so tell us which you need and in what quantity. Wholesale terms, stock position and batch expiry are released to registered professional buyers.

* Professional-use product. Packaging may vary by batch or market. Refer to the supplied IFU for full directions and contraindications.