Dermal Fillers
RESTYLANE references stocked by ALLPARA for professional use, sourced direct and certified on every shipment.
CE Marked
SKU 11099
·
GTIN 761207636824
Restylane Defyne Lidocaine
Restylane Defyne Lidocaine is a dermal filler used to correct moderate to severe deep facial wrinkles and folds and to enhance chin projection and profile. It targets nasolabial folds and other deep lower‑face creases to improve contour while preserving natural facial movement.
In stock
Volume
1 x 1 mL
Laboratory
Galderma Laboratories, L.P.
Origin
Sweden
Indication
Deep wrinkles and folds, chin retrusion
Treatment areas
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Restylane Defyne Lidocaine is a firmer hyaluronic acid filler by Galderma, created to correct deep facial wrinkles and folds while still supporting natural expression. It is commonly applied by clinics, dermatologists and aesthetic physicians to nasolabial folds and to chin projection. The clear, homogeneous gel is crosslinked sodium hyaluronate at 20 mg/mL with 3 mg/mL lidocaine hydrochloride, and it is intended for professional use only.
Key Benefits of Restylane Defyne Lidocaine
- Firm gel for the correction of severe facial wrinkles and folds such as nasolabial folds and marionette lines
- Retains a flexible gel structure, so natural facial movement and expression are preserved despite the added firmness
- Adds volume to the tissue, restoring the skin contours of the face, through the ability of cross-linked hyaluronic acid to bind water
- In a randomised controlled study in nasolabial folds, 69,8% of subjects maintained a significant clinical improvement at 48 weeks
- Contains lidocaine hydrochloride 3 mg/mL, so no separate anaesthetic is needed at the site
- Cross-linked hyaluronic acid at 20 mg/mL, sterilised by moist heat
- Supplied in a blister with two 27G x 1/2 inch ultra thin wall needles and patient record labels
Indications and Professional Use
Main indications
- Severe facial wrinkles and folds, by injection into the mid to deep dermis
- Nasolabial folds
- Marionette lines
Professional use
Restylane Defyne Lidocaine is an injectable medical device for administration exclusively by licensed, appropriately trained healthcare practitioners in a controlled clinical setting, and is not for retail sale or self-administration. It is intended for injection into the mid to deep dermis for the correction of severe facial wrinkles and folds such as nasolabial folds and marionette lines. At a single treatment session, a total volume of 2 ml per nasolabial fold is recommended, and 1 ml for marionette lines. It must not be injected intramuscularly or intravascularly; introduction into the vasculature may lead to embolisation, occlusion of the vessels, ischaemia, or infarction. Injection too superficially, or in facial areas with limited soft tissue support or cover, or thin skin such as the periorbital area, may result in contour irregularities, palpable lumps, or bluish discoloration.
Treatment areas
- Nasolabial folds
- Marionette lines
- Severe facial wrinkles and folds
Patient profile
For adult patients assessed as suitable by the treating practitioner. Patient selection, injected volume, plane and technique follow the practitioner's clinical assessment. Because the gel contains lidocaine hydrochloride 3 mg/mL, patients with known hypersensitivity to lidocaine or to amide-type local anaesthetics must not receive it. It must not be used in patients with a history of hypersensitivity to streptococcal proteins, since the gel may contain trace amounts of such material, in patients with severe allergies manifested by a history of anaphylaxis or a history or presence of multiple severe allergies, or in patients presenting with porphyria. It should be used with caution in patients on immunosuppressive therapy and in patients with a tendency to form hypertrophic scars or other healing disorders. Use should be avoided at sites with active disease, such as inflammation, infection or tumours, until the underlying process has been controlled.
How Restylane Defyne Lidocaine Works
Restylane Defyne Lidocaine works through crosslinked sodium hyaluronate formulated firmer than the Refyne gel, so it can support a deep fold or project the chin while retaining enough flexibility that the tissue still moves naturally. That combination of structure and flexibility is what allows it to be used in the lower face without the result reading as stiff. The incorporated lidocaine hydrochloride reduces discomfort during injection only.
Why Order From Allpara
Allpara offers genuine, verified RESTYLANE products from vetted suppliers, with full batch-traceability and expert support. We serve clinics and aesthetic professionals with CE-certified products, fast EU-wide delivery from our EU warehouse, and competitive trade pricing. Our focus is your patients' safety, satisfaction and results - with dedicated after-sales support for your peace of mind.
Frequently Asked Questions
How does Restylane Defyne Lidocaine differ from Refyne?
Both carry 20 mg/mL cross-linked hyaluronic acid with lidocaine hydrochloride 3 mg/mL, so concentration is not the difference. Defyne is the firmer gel, intended for severe wrinkles and folds including marionette lines, and is supplied with 27G needles. Refyne is softer and more flexible, intended for moderate to severe wrinkles in dynamic areas, and is injected with a 30G needle. The choice follows the depth of correction required.
Which areas is Restylane Defyne Lidocaine used for?
It is intended for the correction of severe facial wrinkles and folds such as nasolabial folds and marionette lines, by injection into the mid to deep dermis. It should not be placed too superficially or in areas with thin skin or limited soft tissue cover, such as the periorbital area.
How do clinics order Restylane Defyne Lidocaine wholesale?
ALLPARA supplies Restylane Defyne Lidocaine to licensed practitioners, clinics and distributors on a B2B account. Defyne and Refyne are usually stocked as a pair since they cover different depths, so state which references and quantities you need. Wholesale terms, stock position and batch expiry are released to registered professional buyers.
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Restylane Defyne Lidocaine
In stock
CE Marked
Restylane Defyne Lidocaine is a firmer hyaluronic acid filler by Galderma, created to correct deep facial wrinkles and folds while still supporting natural expression. It is commonly applied by clinics, dermatologists and aesthetic physicians to nasolabial folds and to chin projection. The clear, homogeneous gel is crosslinked sodium hyaluronate at 20 mg/mL with 3 mg/mL lidocaine hydrochloride, and it is intended for professional use only.
Key Benefits of Restylane Defyne Lidocaine
- Firm gel for the correction of severe facial wrinkles and folds such as nasolabial folds and marionette lines
- Retains a flexible gel structure, so natural facial movement and expression are preserved despite the added firmness
- Adds volume to the tissue, restoring the skin contours of the face, through the ability of cross-linked hyaluronic acid to bind water
- In a randomised controlled study in nasolabial folds, 69,8% of subjects maintained a significant clinical improvement at 48 weeks
- Contains lidocaine hydrochloride 3 mg/mL, so no separate anaesthetic is needed at the site
- Cross-linked hyaluronic acid at 20 mg/mL, sterilised by moist heat
- Supplied in a blister with two 27G x 1/2 inch ultra thin wall needles and patient record labels
Indications and Professional Use
Main indications
- Severe facial wrinkles and folds, by injection into the mid to deep dermis
- Nasolabial folds
- Marionette lines
Professional use
Restylane Defyne Lidocaine is an injectable medical device for administration exclusively by licensed, appropriately trained healthcare practitioners in a controlled clinical setting, and is not for retail sale or self-administration. It is intended for injection into the mid to deep dermis for the correction of severe facial wrinkles and folds such as nasolabial folds and marionette lines. At a single treatment session, a total volume of 2 ml per nasolabial fold is recommended, and 1 ml for marionette lines. It must not be injected intramuscularly or intravascularly; introduction into the vasculature may lead to embolisation, occlusion of the vessels, ischaemia, or infarction. Injection too superficially, or in facial areas with limited soft tissue support or cover, or thin skin such as the periorbital area, may result in contour irregularities, palpable lumps, or bluish discoloration.
Treatment areas
- Nasolabial folds
- Marionette lines
- Severe facial wrinkles and folds
Patient profile
For adult patients assessed as suitable by the treating practitioner. Patient selection, injected volume, plane and technique follow the practitioner's clinical assessment. Because the gel contains lidocaine hydrochloride 3 mg/mL, patients with known hypersensitivity to lidocaine or to amide-type local anaesthetics must not receive it. It must not be used in patients with a history of hypersensitivity to streptococcal proteins, since the gel may contain trace amounts of such material, in patients with severe allergies manifested by a history of anaphylaxis or a history or presence of multiple severe allergies, or in patients presenting with porphyria. It should be used with caution in patients on immunosuppressive therapy and in patients with a tendency to form hypertrophic scars or other healing disorders. Use should be avoided at sites with active disease, such as inflammation, infection or tumours, until the underlying process has been controlled.
How Restylane Defyne Lidocaine Works
Restylane Defyne Lidocaine works through crosslinked sodium hyaluronate formulated firmer than the Refyne gel, so it can support a deep fold or project the chin while retaining enough flexibility that the tissue still moves naturally. That combination of structure and flexibility is what allows it to be used in the lower face without the result reading as stiff. The incorporated lidocaine hydrochloride reduces discomfort during injection only.
Why Order From Allpara
Allpara offers genuine, verified RESTYLANE products with full batch-traceability, CE-certified stock, fast EU-wide delivery and expert after-sales support.
Frequently Asked Questions
How does Restylane Defyne Lidocaine differ from Refyne?
Both carry 20 mg/mL cross-linked hyaluronic acid with lidocaine hydrochloride 3 mg/mL, so concentration is not the difference. Defyne is the firmer gel, intended for severe wrinkles and folds including marionette lines, and is supplied with 27G needles. Refyne is softer and more flexible, intended for moderate to severe wrinkles in dynamic areas, and is injected with a 30G needle. The choice follows the depth of correction required.
Which areas is Restylane Defyne Lidocaine used for?
It is intended for the correction of severe facial wrinkles and folds such as nasolabial folds and marionette lines, by injection into the mid to deep dermis. It should not be placed too superficially or in areas with thin skin or limited soft tissue cover, such as the periorbital area.
How do clinics order Restylane Defyne Lidocaine wholesale?
ALLPARA supplies Restylane Defyne Lidocaine to licensed practitioners, clinics and distributors on a B2B account. Defyne and Refyne are usually stocked as a pair since they cover different depths, so state which references and quantities you need. Wholesale terms, stock position and batch expiry are released to registered professional buyers.
More from Galderma
View laboratory →* Professional-use product. Packaging may vary by batch or market. Refer to the supplied IFU for full directions and contraindications.