Pluryal Classic

Pluryal Classic is a monophasic, cross-linked hyaluronic acid dermal filler from the Pluryal Fillers Essentials range, manufactured by MD Skin Solutions Laboratoires in Luxembourg. The Pluryal Classic filler is formulated at 2.3% (23 mg/mL) hyaluronic acid of non-animal origin, obtained from Streptococcus equi bacteria and cross-linked with BDDE to a residual level of ≤ 2 ppm in a phosphate buffer with NaCl. It is indicated for the correction of moderate to severe nasolabial folds, and for cosmetic and medical reconstructive purposes such as facial lipoatrophy, debilitating scars and morphological asymmetry. With an elastic modulus (G’) of 195,000 mPa and a 10 N extrusion force, it is injected into the mid to deep dermis, with treatment repeated every 5-6 months or as required. Practitioners looking to buy Pluryal Classic should note that it is supplied as 1 x 1 mL.

• Hyaluronic acid at 2.3% (23 mg/mL), monophasic and free from particles for uniform degradation without the need to over-correct
• Cross-linked with BDDE to a residual level of ≤ 2 ppm, with endotoxins < 0.5 EU/mL
• G’ of 195,000 mPa — superior to competitors with comparable viscosity and indications — for filling effect and retention time in soft tissue
• Low extrusion force of 10 N, tested on every batch, in a syringe design awarded the iF Design Award 2017
• Efficacy maintained six months after injection in published clinical studies
• Smooth, natural feel to the touch and sight; isotonic for improved comfort during treatment
• Intended for professional injectable use only

Indications and Professional Use

Main indications

• Correction of moderate to severe nasolabial folds
• Cosmetic and medical reconstructive treatment of facial lipoatrophy
• Debilitating scars
• Morphological asymmetry

Professional use

Pluryal Classic is a class III medical device, to be used only by doctors who have received specific training on intradermal injection techniques. Composition and specification: cross-linked hyaluronic acid 2.3% (23 mg/mL) obtained from Streptococcus equi, phosphate buffer, NaCl; BDDE cross-linked (≤ 2 ppm); molecular weight 3 million Da; G’ 195,000 mPa; extrusion force 10 N; endotoxins < 0.5 EU/mL; steam sterilized. Level of injection: mid to deep dermis. Treatment frequency: every 5-6 months or as required. Read the Instructions For Use supplied with the product before treatment, and inform patients about possible side effects.

Treatment areas

• Nasolabial folds — the reference's own labelled indication
• Bitterness lines
• Glabellar lines
• Jawline
• Cheeks
• Skin texture
• Neck
• Hands
• Décolleté
• Beyond nasolabial folds, the areas above are those listed by the manufacturer as target areas for the Pluryal Fillers Essentials range, of which Pluryal Classic is part, rather than for this single reference.

Patient profile

Adult patients presenting moderate to severe nasolabial folds, or requiring cosmetic or reconstructive correction of facial lipoatrophy, debilitating scars or morphological asymmetry, as assessed by the treating doctor. Pluryal Classic is a class III medical device restricted to doctors trained in intradermal injection techniques, and patients must be informed about possible side effects. Patient selection, including contraindications and precautions, must be determined per the manufacturer’s Instructions For Use supplied with the product.

How Pluryal Classic Works

Why Order From Allpara

Allpara offers genuine, verified PLURYAL products from vetted suppliers, with full batch-traceability and expert support. We serve clinics and aesthetic professionals with CE-certified products, fast EU-wide delivery from our EU warehouse, and competitive trade pricing. Our focus is your patients' safety, satisfaction and results - with dedicated after-sales support for your peace of mind.

Frequently Asked Questions