PLURYAL references stocked by ALLPARA for professional use, sourced direct and certified on every shipment.
Pluryal Silk
Pluryal Silk is a polynucleotide (PN) skin biostimulator by PLURYAL, specifically formulated for delicate skin zones such as the peri-orbital and peri-oral areas. It is indicated for under-eye wrinkles, crow's feet and dark circles, as well as scars and stretch marks. The product contains 15 mg of polynucleotides per 2 mL syringe (7.5 mg/mL) and is a sterile, CE-marked class III medical device for professional intradermal use only.
Key Benefits of Pluryal Silk
- Stimulates cellular repair and skin regeneration in delicate zones
- Modulates inflammation, reducing redness over the long term
- Induces collagen to improve firmness and skin density
- Gentle PN formulation at 7.5 mg/mL, suited to sensitive areas including the under-eye and lips
- CE-marked Class III medical device for professional use
Indications and Professional Use
Main indications
- Priming and repairing treatment for thin, delicate skin
- Under-eye wrinkles and crow's feet
- Dark circles
- Dilated pores
- Scars, including acne scars
- Stretch marks
Professional use
For use by licensed medical practitioners only. Pluryal Silk is a class III medical device administered by intradermal injection into the deep dermis (mid dermis around the lips and eyes) of thin, delicate skin areas, following clinical assessment, using the multi-puncture, micro-droplet or point-by-point technique. Recommended protocol: one session every 21 days, three sessions in total, with maintenance every 6 months.
Treatment areas
- Peri-orbital region (eyelids, dark circles, crow's feet) and peri-oral region
- Neck and décolleté
- Body: inner arms, chest, abdomen
Patient profile
Suitable for adult patients seeking regeneration of delicate or thin skin — peri-orbital, peri-oral, neck, décolleté and body — and treatment of scars or stretch marks, as assessed by a medical practitioner. In a prospective observational study (Journal of Cosmetic Dermatology, 2026) — a single-centre, uncontrolled series of 42 patients aged 25–65, 38 of whom were followed up at 6 months — intradermal Pluryal Silk injections, two sessions three weeks apart, were associated with significant improvement of under-eye wrinkles and crow's feet at every follow-up, peaking at three months (FACE-Q appraisal improved by 9.5 points for the lower eyelids and by 10.6 points for crow's feet, p < 0.001), with minimal adverse events.
How Pluryal Silk Works
Pluryal Silk works through a gentle polynucleotide (PN) formulation at 7.5 mg/mL — SALMOSTIM® polynucleotides extracted from controlled, certified farmed salmon milt — injected intradermally to stimulate fibroblast-driven cellular repair, modulate inflammation and induce collagen synthesis in delicate skin zones. A prospective observational study in 42 patients treated for under-eye wrinkles and crow's feet showed improvement peaking at three months, and an ex-vivo human-skin study showed a significant 7% increase in total collagen content in the papillary and upper reticular dermis at day 9 (p < 0.01) — a very good result for this parameter, where increases usually range from 5 to 8% because the dermis already holds a high quantity of total collagen — supporting the biostimulatory action of polynucleotides at the dermal level.
Why Order From Allpara
Allpara offers genuine, verified PLURYAL products from vetted suppliers, with full batch-traceability and expert support. We serve clinics and aesthetic professionals with CE-certified products, fast EU-wide delivery from our EU warehouse, and competitive trade pricing. Our focus is your patients' safety, satisfaction and results - with dedicated after-sales support for your peace of mind.
Frequently Asked Questions
Is Pluryal Silk suitable for the under-eye area?
Yes. Pluryal Silk is specifically formulated for delicate zones including the peri-orbital area, and is indicated for under-eye wrinkles, crow's feet and dark circles.
Does Pluryal Silk contain hyaluronic acid?
No. Pluryal Silk is a polynucleotide (PN) biostimulator, not a hyaluronic acid filler. It contains 15 mg of polynucleotides per syringe at a concentration of 7.5 mg/mL.
Which areas can Pluryal Silk treat?
Pluryal Silk is indicated for priming and repairing thin, fragile skin areas, under-eye wrinkles, crow's feet, dark circles, scars (including acne scars) and stretch marks, across the peri-orbital and peri-oral regions, neck, décolleté and body.
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Pluryal Silk
Pluryal Silk is a polynucleotide (PN) skin biostimulator by PLURYAL, specifically formulated for delicate skin zones such as the peri-orbital and peri-oral areas. It is indicated for under-eye wrinkles, crow's feet and dark circles, as well as scars and stretch marks. The product contains 15 mg of polynucleotides per 2 mL syringe (7.5 mg/mL) and is a sterile, CE-marked class III medical device for professional intradermal use only.
Key Benefits of Pluryal Silk
- Stimulates cellular repair and skin regeneration in delicate zones
- Modulates inflammation, reducing redness over the long term
- Induces collagen to improve firmness and skin density
- Gentle PN formulation at 7.5 mg/mL, suited to sensitive areas including the under-eye and lips
- CE-marked Class III medical device for professional use
Indications and Professional Use
Main indications
- Priming and repairing treatment for thin, delicate skin
- Under-eye wrinkles and crow's feet
- Dark circles
- Dilated pores
- Scars, including acne scars
- Stretch marks
Professional use
For use by licensed medical practitioners only. Pluryal Silk is a class III medical device administered by intradermal injection into the deep dermis (mid dermis around the lips and eyes) of thin, delicate skin areas, following clinical assessment, using the multi-puncture, micro-droplet or point-by-point technique. Recommended protocol: one session every 21 days, three sessions in total, with maintenance every 6 months.
Treatment areas
- Peri-orbital region (eyelids, dark circles, crow's feet) and peri-oral region
- Neck and décolleté
- Body: inner arms, chest, abdomen
Patient profile
Suitable for adult patients seeking regeneration of delicate or thin skin — peri-orbital, peri-oral, neck, décolleté and body — and treatment of scars or stretch marks, as assessed by a medical practitioner. In a prospective observational study (Journal of Cosmetic Dermatology, 2026) — a single-centre, uncontrolled series of 42 patients aged 25–65, 38 of whom were followed up at 6 months — intradermal Pluryal Silk injections, two sessions three weeks apart, were associated with significant improvement of under-eye wrinkles and crow's feet at every follow-up, peaking at three months (FACE-Q appraisal improved by 9.5 points for the lower eyelids and by 10.6 points for crow's feet, p < 0.001), with minimal adverse events.
How Pluryal Silk Works
Pluryal Silk works through a gentle polynucleotide (PN) formulation at 7.5 mg/mL — SALMOSTIM® polynucleotides extracted from controlled, certified farmed salmon milt — injected intradermally to stimulate fibroblast-driven cellular repair, modulate inflammation and induce collagen synthesis in delicate skin zones. A prospective observational study in 42 patients treated for under-eye wrinkles and crow's feet showed improvement peaking at three months, and an ex-vivo human-skin study showed a significant 7% increase in total collagen content in the papillary and upper reticular dermis at day 9 (p < 0.01) — a very good result for this parameter, where increases usually range from 5 to 8% because the dermis already holds a high quantity of total collagen — supporting the biostimulatory action of polynucleotides at the dermal level.
Why Order From Allpara
Allpara offers genuine, verified PLURYAL products with full batch-traceability, CE-certified stock, fast EU-wide delivery and expert after-sales support.
Frequently Asked Questions
Is Pluryal Silk suitable for the under-eye area?
Yes. Pluryal Silk is specifically formulated for delicate zones including the peri-orbital area, and is indicated for under-eye wrinkles, crow's feet and dark circles.
Does Pluryal Silk contain hyaluronic acid?
No. Pluryal Silk is a polynucleotide (PN) biostimulator, not a hyaluronic acid filler. It contains 15 mg of polynucleotides per syringe at a concentration of 7.5 mg/mL.
Which areas can Pluryal Silk treat?
Pluryal Silk is indicated for priming and repairing thin, fragile skin areas, under-eye wrinkles, crow's feet, dark circles, scars (including acne scars) and stretch marks, across the peri-orbital and peri-oral regions, neck, décolleté and body.