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· Biorevitalisation
SKU 11042 · GTIN 5040000058699

Pluryal Silk

In stock
Volume
1 x 2 mL
Laboratory
MD Skin solutions Laboratoires
Origin
Luxemburg
Indication
Dark circles; under-eye wrinkles; crow's feet; skin priming and repair
Trade price and history are verified-only
allpara supplies licensed practitioners. Sign in or apply for a B2B account to see live pricing, volume tiers and price history.

Pluryal Silk is a polynucleotide (PN) skin biostimulator by PLURYAL, specifically formulated for delicate skin zones such as the peri-orbital and peri-oral areas. It is indicated for under-eye wrinkles, crow's feet and dark circles, as well as scars and stretch marks. The product contains 15 mg of polynucleotides per 2 mL syringe (7.5 mg/mL) and is a sterile, CE-marked class III medical device for professional intradermal use only.

Key Benefits of Pluryal Silk

  • Stimulates cellular repair and skin regeneration in delicate zones
  • Modulates inflammation, reducing redness over the long term
  • Induces collagen to improve firmness and skin density
  • Gentle PN formulation at 7.5 mg/mL, suited to sensitive areas including the under-eye and lips
  • CE-marked Class III medical device for professional use
Key Information
Brand Pluryal
Manufacturer MD Skin Solutions
Country of Origin Luxembourg
Certification CE-marked Class III medical device
Ingredients Polynucleotides (PN) 15 mg per 2 mL syringe (7.5 mg/mL)
Packaging 1 prefilled 2 mL syringe, supplied with 2 x 30G ½″ injection needles
Use Type Professional use only – injectable polynucleotide (PN) biostimulator for delicate skin areas
Injection Depth Intradermal (deep dermis; mid dermis around the lips and eyes)
Protocol / Duration 1 session every 21 days, 3 sessions total; maintenance repeated every 6 months

Indications and Professional Use

Main indications

  • Priming and repairing treatment for thin, delicate skin
  • Under-eye wrinkles and crow's feet
  • Dark circles
  • Dilated pores
  • Scars, including acne scars
  • Stretch marks

Professional use

For use by licensed medical practitioners only. Pluryal Silk is a class III medical device administered by intradermal injection into the deep dermis (mid dermis around the lips and eyes) of thin, delicate skin areas, following clinical assessment, using the multi-puncture, micro-droplet or point-by-point technique. Recommended protocol: one session every 21 days, three sessions in total, with maintenance every 6 months.

Treatment areas

  • Peri-orbital region (eyelids, dark circles, crow's feet) and peri-oral region
  • Neck and décolleté
  • Body: inner arms, chest, abdomen

Patient profile

Suitable for adult patients seeking regeneration of delicate or thin skin — peri-orbital, peri-oral, neck, décolleté and body — and treatment of scars or stretch marks, as assessed by a medical practitioner. In a prospective observational study (Journal of Cosmetic Dermatology, 2026) — a single-centre, uncontrolled series of 42 patients aged 25–65, 38 of whom were followed up at 6 months — intradermal Pluryal Silk injections, two sessions three weeks apart, were associated with significant improvement of under-eye wrinkles and crow's feet at every follow-up, peaking at three months (FACE-Q appraisal improved by 9.5 points for the lower eyelids and by 10.6 points for crow's feet, p < 0.001), with minimal adverse events.

How Pluryal Silk Works

Pluryal Silk works through a gentle polynucleotide (PN) formulation at 7.5 mg/mL — SALMOSTIM® polynucleotides extracted from controlled, certified farmed salmon milt — injected intradermally to stimulate fibroblast-driven cellular repair, modulate inflammation and induce collagen synthesis in delicate skin zones. A prospective observational study in 42 patients treated for under-eye wrinkles and crow's feet showed improvement peaking at three months, and an ex-vivo human-skin study showed a significant 7% increase in total collagen content in the papillary and upper reticular dermis at day 9 (p < 0.01) — a very good result for this parameter, where increases usually range from 5 to 8% because the dermis already holds a high quantity of total collagen — supporting the biostimulatory action of polynucleotides at the dermal level.

Why Order From Allpara

Allpara offers genuine, verified PLURYAL products from vetted suppliers, with full batch-traceability and expert support. We serve clinics and aesthetic professionals with CE-certified products, fast EU-wide delivery from our EU warehouse, and competitive trade pricing. Our focus is your patients' safety, satisfaction and results - with dedicated after-sales support for your peace of mind.

Frequently Asked Questions

Is Pluryal Silk suitable for the under-eye area?

Yes. Pluryal Silk is specifically formulated for delicate zones including the peri-orbital area, and is indicated for under-eye wrinkles, crow's feet and dark circles.

Does Pluryal Silk contain hyaluronic acid?

No. Pluryal Silk is a polynucleotide (PN) biostimulator, not a hyaluronic acid filler. It contains 15 mg of polynucleotides per syringe at a concentration of 7.5 mg/mL.

Which areas can Pluryal Silk treat?

Pluryal Silk is indicated for priming and repairing thin, fragile skin areas, under-eye wrinkles, crow's feet, dark circles, scars (including acne scars) and stretch marks, across the peri-orbital and peri-oral regions, neck, décolleté and body.

/ Specifications

The datasheet

Brand
PLURYAL
Laboratory
MD Skin solutions Laboratoires
SKU
11042
GTIN
5040000058699
Format
1 x 2 mL
Origin
Luxemburg
Indication
Dark circles; under-eye wrinkles; crow's feet; skin priming and repair
Use
Professional, intradermal injection
/ Product details

The full file

Pluryal Silk is a polynucleotide (PN) skin biostimulator by PLURYAL, specifically formulated for delicate skin zones such as the peri-orbital and peri-oral areas. It is indicated for under-eye wrinkles, crow's feet and dark circles, as well as scars and stretch marks. The product contains 15 mg of polynucleotides per 2 mL syringe (7.5 mg/mL) and is a sterile, CE-marked class III medical device for professional intradermal use only.

MD Skin solutions Laboratoires, country of origin Luxemburg.

Shipped EU-wide from our EU warehouse, tracked and insured, with 24-72h dispatch. Each unit ships with batch number and expiry, held in EU bond and batch-traceable.

Store to manufacturer specification, away from direct light. Cold-chain is only used where the product requires it.

Net 30 / 60 / 90 day terms* are available to verified accounts on credit approval. Invoicing is supported in EUR, CHF and GBP.

Terms are indicative and confirmed after account review.

Is Pluryal Silk suitable for the under-eye area?

Yes. Pluryal Silk is specifically formulated for delicate zones including the peri-orbital area, and is indicated for under-eye wrinkles, crow's feet and dark circles.

Does Pluryal Silk contain hyaluronic acid?

No. Pluryal Silk is a polynucleotide (PN) biostimulator, not a hyaluronic acid filler. It contains 15 mg of polynucleotides per syringe at a concentration of 7.5 mg/mL.

Which areas can Pluryal Silk treat?

Pluryal Silk is indicated for priming and repairing thin, fragile skin areas, under-eye wrinkles, crow's feet, dark circles, scars (including acne scars) and stretch marks, across the peri-orbital and peri-oral regions, neck, décolleté and body.

/ Quick answers

Everything a buyer asks first

Is Pluryal Silk suitable for the under-eye area?
Yes. Pluryal Silk is specifically formulated for delicate zones including the peri-orbital area, and is indicated for under-eye wrinkles, crow's feet and dark circles.
Does Pluryal Silk contain hyaluronic acid?
No. Pluryal Silk is a polynucleotide (PN) biostimulator, not a hyaluronic acid filler. It contains 15 mg of polynucleotides per syringe at a concentration of 7.5 mg/mL.
Which areas can Pluryal Silk treat?
Pluryal Silk is indicated for priming and repairing thin, fragile skin areas, under-eye wrinkles, crow's feet, dark circles, scars (including acne scars) and stretch marks, across the peri-orbital and peri-oral regions, neck, décolleté and body.
/ FAQ

Frequently asked

Yes. Pluryal Silk is specifically formulated for delicate zones including the peri-orbital area, and is indicated for under-eye wrinkles, crow's feet and dark circles.
No. Pluryal Silk is a polynucleotide (PN) biostimulator, not a hyaluronic acid filler. It contains 15 mg of polynucleotides per syringe at a concentration of 7.5 mg/mL.
Pluryal Silk is indicated for priming and repairing thin, fragile skin areas, under-eye wrinkles, crow's feet, dark circles, scars (including acne scars) and stretch marks, across the peri-orbital and peri-oral regions, neck, décolleté and body.

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Pluryal Silk

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Pluryal Silk is a polynucleotide (PN) skin biostimulator by PLURYAL, specifically formulated for delicate skin zones such as the peri-orbital and peri-oral areas. It is indicated for under-eye wrinkles, crow's feet and dark circles, as well as scars and stretch marks. The product contains 15 mg of polynucleotides per 2 mL syringe (7.5 mg/mL) and is a sterile, CE-marked class III medical device for professional intradermal use only.

Key Benefits of Pluryal Silk

  • Stimulates cellular repair and skin regeneration in delicate zones
  • Modulates inflammation, reducing redness over the long term
  • Induces collagen to improve firmness and skin density
  • Gentle PN formulation at 7.5 mg/mL, suited to sensitive areas including the under-eye and lips
  • CE-marked Class III medical device for professional use
Key Information
Brand Pluryal
Manufacturer MD Skin Solutions
Country of Origin Luxembourg
Certification CE-marked Class III medical device
Ingredients Polynucleotides (PN) 15 mg per 2 mL syringe (7.5 mg/mL)
Packaging 1 prefilled 2 mL syringe, supplied with 2 x 30G ½″ injection needles
Use Type Professional use only – injectable polynucleotide (PN) biostimulator for delicate skin areas
Injection Depth Intradermal (deep dermis; mid dermis around the lips and eyes)
Protocol / Duration 1 session every 21 days, 3 sessions total; maintenance repeated every 6 months

Indications and Professional Use

Main indications

  • Priming and repairing treatment for thin, delicate skin
  • Under-eye wrinkles and crow's feet
  • Dark circles
  • Dilated pores
  • Scars, including acne scars
  • Stretch marks

Professional use

For use by licensed medical practitioners only. Pluryal Silk is a class III medical device administered by intradermal injection into the deep dermis (mid dermis around the lips and eyes) of thin, delicate skin areas, following clinical assessment, using the multi-puncture, micro-droplet or point-by-point technique. Recommended protocol: one session every 21 days, three sessions in total, with maintenance every 6 months.

Treatment areas

  • Peri-orbital region (eyelids, dark circles, crow's feet) and peri-oral region
  • Neck and décolleté
  • Body: inner arms, chest, abdomen

Patient profile

Suitable for adult patients seeking regeneration of delicate or thin skin — peri-orbital, peri-oral, neck, décolleté and body — and treatment of scars or stretch marks, as assessed by a medical practitioner. In a prospective observational study (Journal of Cosmetic Dermatology, 2026) — a single-centre, uncontrolled series of 42 patients aged 25–65, 38 of whom were followed up at 6 months — intradermal Pluryal Silk injections, two sessions three weeks apart, were associated with significant improvement of under-eye wrinkles and crow's feet at every follow-up, peaking at three months (FACE-Q appraisal improved by 9.5 points for the lower eyelids and by 10.6 points for crow's feet, p < 0.001), with minimal adverse events.

How Pluryal Silk Works

Pluryal Silk works through a gentle polynucleotide (PN) formulation at 7.5 mg/mL — SALMOSTIM® polynucleotides extracted from controlled, certified farmed salmon milt — injected intradermally to stimulate fibroblast-driven cellular repair, modulate inflammation and induce collagen synthesis in delicate skin zones. A prospective observational study in 42 patients treated for under-eye wrinkles and crow's feet showed improvement peaking at three months, and an ex-vivo human-skin study showed a significant 7% increase in total collagen content in the papillary and upper reticular dermis at day 9 (p < 0.01) — a very good result for this parameter, where increases usually range from 5 to 8% because the dermis already holds a high quantity of total collagen — supporting the biostimulatory action of polynucleotides at the dermal level.

Why Order From Allpara

Allpara offers genuine, verified PLURYAL products with full batch-traceability, CE-certified stock, fast EU-wide delivery and expert after-sales support.

Frequently Asked Questions

Is Pluryal Silk suitable for the under-eye area?

Yes. Pluryal Silk is specifically formulated for delicate zones including the peri-orbital area, and is indicated for under-eye wrinkles, crow's feet and dark circles.

Does Pluryal Silk contain hyaluronic acid?

No. Pluryal Silk is a polynucleotide (PN) biostimulator, not a hyaluronic acid filler. It contains 15 mg of polynucleotides per syringe at a concentration of 7.5 mg/mL.

Which areas can Pluryal Silk treat?

Pluryal Silk is indicated for priming and repairing thin, fragile skin areas, under-eye wrinkles, crow's feet, dark circles, scars (including acne scars) and stretch marks, across the peri-orbital and peri-oral regions, neck, décolleté and body.

More from MD Skin solutions Laboratoires

View laboratory →

Pluryal Silk is a polynucleotide (PN) skin biostimulator by PLURYAL, specifically formulated for delicate skin zones such as the peri-orbital and peri-oral areas. It is indicated for under-eye wrinkles, crow's feet and dark circles, as well as scars and stretch marks. The product contains 15 mg of polynucleotides per 2 mL syringe (7.5 mg/mL) and is a sterile, CE-marked class III medical device for professional intradermal use only.

MD Skin solutions Laboratoires, country of origin Luxemburg.

Shipped EU-wide from our EU warehouse, 24-72h dispatch, tracked and insured. Each unit ships with batch number and expiry, held in EU bond and batch-traceable. Store to manufacturer specification.

Net 30 / 60 / 90 day terms* for verified accounts on credit approval. Invoicing in EUR, CHF and GBP.

Is Pluryal Silk suitable for the under-eye area?

Yes. Pluryal Silk is specifically formulated for delicate zones including the peri-orbital area, and is indicated for under-eye wrinkles, crow's feet and dark circles.

Does Pluryal Silk contain hyaluronic acid?

No. Pluryal Silk is a polynucleotide (PN) biostimulator, not a hyaluronic acid filler. It contains 15 mg of polynucleotides per syringe at a concentration of 7.5 mg/mL.

Which areas can Pluryal Silk treat?

Pluryal Silk is indicated for priming and repairing thin, fragile skin areas, under-eye wrinkles, crow's feet, dark circles, scars (including acne scars) and stretch marks, across the peri-orbital and peri-oral regions, neck, décolleté and body.

* Professional-use product. Packaging may vary by batch or market. Refer to the supplied IFU for full directions and contraindications.